Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.1
USERS' SCORE
Good
Based on 5 Reviews
8.5
Supplement Facts
Serving Size:  2 Soft Gels
Amount Per Serving
%DV
Calories
10
 
Total Fat
1 g
1%
Saturated Fat
0 g
0%
Trans Fat
0 g
Vitamin D3 (cholecalciferol)
10 mcg (400 IU)
67%
Total Omega-3s♦
830 mg
EPA (Eicosapentaenoic Acid)
205 mg
DHA (Docosahexaenoic Acid)
480 mg

Top Medical Research Studies

9.5
Eicosapentaenoic acid benefits CFS
We explored the potential benefits of eicosapentaenoic acid (EPA), an essential fatty acid, in treating chronic fatigue syndrome (CFS). A female patient with a six-year history of persistent CFS symptoms participated in the study, receiving a daily supplement rich in EPA.

After measuring her brain structure through high-resolution magnetic resonance imaging both at the beginning and 16 weeks later, we observed significant improvements in her symptoms starting just six to eight weeks into the treatment. Most notably, the patient's lateral ventricular volume—a key indicator of brain health—decreased from 28,940 mm³ to 23,660 mm³, indicating structural changes in her brain.

This research hints at the promising role of EPA in alleviating symptoms of chronic fatigue syndrome while also suggesting positive brain changes associated with treatment. The findings encourage further investigation into fatty acid supplementation's potential as an effective therapeutic strategy for CFS.
Read More
9
Eicosapentaenoic acid shows promise
We examined the link between chronic fatigue syndrome (CFS) and essential fatty acids, focusing specifically on eicosapentaenoic acid (EPA). This investigation arose from various studies highlighting the potential role essential fatty acids play in alleviating symptoms associated with CFS.

Our approach involved administering a high-EPA supplementation to a group of individuals diagnosed with chronic fatigue syndrome. After following these patients for eight to twelve weeks, we observed that all participants experienced notable improvements in their symptoms.

These positive changes align with recent findings that discuss both cerebral and clinical benefits tied to increased EPA intake. Given these encouraging results, eicosapentaenoic acid may ultimately provide hope for many suffering from chronic fatigue syndrome.
Read More
We conducted a thorough investigation into whether high-dose intermittent vitamin D3 could alleviate symptoms of chronic fatigue syndrome (CFS) and improve vascular health. This double-blind, randomized placebo-controlled trial involved patients meeting established criteria for CFS. Participants received either 100,000 units of vitamin D3 or a placebo every two months for six months.

Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.

In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.
Read More

Most Useful Reviews

9
Improved energy levels
34 people found this helpful
The effect is clear. Since I began taking Omega and Vitamin D while breastfeeding my 2-month-old daughter, my fatigue and sleepiness have significantly lessened. I feel lively and no longer struggle to stay awake during the day. My hair remains healthy, and I’ve had no acne issues, which I was concerned about. I will continue taking these supplements as they truly boost my wellbeing.
Read More
9
Healthy baby outcome
I was diagnosed with Down syndrome and experienced complications during my pregnancy. Despite a difficult time, I regularly took this Omega 3 without any unpleasant side effects. It contributed significantly to my health, helping to protect against chronic fatigue syndrome, and I’m thrilled to have delivered a healthy baby. It's undoubtedly worth investing in these vital vitamins during pregnancy.
Read More
7.5
Boosted cheerfulness
4 people found this helpful
This prenatal Omega with Vitamin D3 is great for pregnant and lactating women, ensuring proper brain development for the baby. The small capsules are easy to swallow with no fishy taste, and I’ve experienced no side effects. After taking them, I feel cheerful, which helps counteract chronic fatigue syndrome during this vital time.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.1
  • All Researches
9.5
Eicosapentaenoic acid benefits CFS
We explored the potential benefits of eicosapentaenoic acid (EPA), an essential fatty acid, in treating chronic fatigue syndrome (CFS). A female patient with a six-year history of persistent CFS symptoms participated in the study, receiving a daily supplement rich in EPA.

After measuring her brain structure through high-resolution magnetic resonance imaging both at the beginning and 16 weeks later, we observed significant improvements in her symptoms starting just six to eight weeks into the treatment. Most notably, the patient's lateral ventricular volume—a key indicator of brain health—decreased from 28,940 mm³ to 23,660 mm³, indicating structural changes in her brain.

This research hints at the promising role of EPA in alleviating symptoms of chronic fatigue syndrome while also suggesting positive brain changes associated with treatment. The findings encourage further investigation into fatty acid supplementation's potential as an effective therapeutic strategy for CFS.
Read More
9
Eicosapentaenoic acid shows promise
We examined the link between chronic fatigue syndrome (CFS) and essential fatty acids, focusing specifically on eicosapentaenoic acid (EPA). This investigation arose from various studies highlighting the potential role essential fatty acids play in alleviating symptoms associated with CFS.

Our approach involved administering a high-EPA supplementation to a group of individuals diagnosed with chronic fatigue syndrome. After following these patients for eight to twelve weeks, we observed that all participants experienced notable improvements in their symptoms.

These positive changes align with recent findings that discuss both cerebral and clinical benefits tied to increased EPA intake. Given these encouraging results, eicosapentaenoic acid may ultimately provide hope for many suffering from chronic fatigue syndrome.
Read More
9
Effective treatment for fatigue syndrome
We conducted a thorough investigation into the effects of essential fatty acids, including eicosapentaenoic acid (EPA), on individuals suffering from postviral fatigue syndrome. In a well-structured trial, 63 adults with this condition participated in a double-blind, placebo-controlled study. They had been living with severe fatigue and other troubling symptoms for one to three years following a viral infection.

Patients received either an active treatment containing EPA and other essential fatty acids or a placebo for three months. Their overall health, fatigue levels, and other symptoms were assessed at the beginning, after one month, and at the end of the study. Strikingly, we observed that 74% of those taking the essential fatty acids reported improvements after one month, rising to 85% after three months. In contrast, only 23% and 17% of the placebo group noted any benefit at those respective time points.

Notably, the fatty acid levels in the participants' red blood cells, which were abnormal at the beginning of the trial, showed significant improvement with the active treatment. Importantly, we found no adverse side effects from the treatment, leading us to conclude that essential fatty acids can be a safe and effective option for people dealing with postviral fatigue syndrome.
Read More
8
Beta-glucan shows cognitive improvements
We conducted a randomized, double-blind, placebo-controlled trial to explore how yeast beta-glucan, along with multivitamins, affects individuals suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In our study, 65 participants received either beta-glucan combined with vitamins and zinc or a placebo for 36 weeks.

Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.

Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.
Read More
8
Eicosapentaenoic acid's potential in CFS
We explored the connection between eicosapentaenoic acid (EPA) and chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis. The research indicates that individuals suffering from CFS may experience complications linked to persistent viral infections, which could hinder their body's ability to produce necessary fatty acids.

Specifically, the issue revolves around the enzyme delta-6 desaturase, which plays a critical role in the conversion of essential fatty acids like alpha-linolenic acid and linoleic acid into longer chain polyunsaturated fatty acids. These fatty acids are vital for maintaining healthy cell membranes and proper cell signaling. If their production is inhibited, it could explain many symptoms associated with CFS.

One intriguing aspect we observed is the potential therapeutic role that EPA could play. By providing EPA directly, we may bypass some of the metabolic restrictions caused by viral infections. This not only aids in generating essential fatty acids needed for bodily functions but also shows promise as a treatment option that could alleviate certain symptoms of CFS.

While the exact impact of EPA treatment on CFS warrants further investigation, the findings suggest that it might offer some benefits worth considering for those affected by this challenging condition.
Read More

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Improved energy levels
34 people found this helpful
The effect is clear. Since I began taking Omega and Vitamin D while breastfeeding my 2-month-old daughter, my fatigue and sleepiness have significantly lessened. I feel lively and no longer struggle to stay awake during the day. My hair remains healthy, and I’ve had no acne issues, which I was concerned about. I will continue taking these supplements as they truly boost my wellbeing.
Read More
9
Healthy baby outcome
I was diagnosed with Down syndrome and experienced complications during my pregnancy. Despite a difficult time, I regularly took this Omega 3 without any unpleasant side effects. It contributed significantly to my health, helping to protect against chronic fatigue syndrome, and I’m thrilled to have delivered a healthy baby. It's undoubtedly worth investing in these vital vitamins during pregnancy.
Read More
7.5
Boosted cheerfulness
4 people found this helpful
This prenatal Omega with Vitamin D3 is great for pregnant and lactating women, ensuring proper brain development for the baby. The small capsules are easy to swallow with no fishy taste, and I’ve experienced no side effects. After taking them, I feel cheerful, which helps counteract chronic fatigue syndrome during this vital time.
Read More
7.5
Enhanced wellbeing
10 people found this helpful
This Omega product for mothers is excellent. The small, easy-to-swallow tablets have no unpleasant flavours. I can feel the advantages of Omega-3, which supports vital bodily functions and combats chronic fatigue syndrome. It has helped improve my energy levels and overall health, so I highly recommend it.
Read More
7.5
Healthy hair growth
During my third pregnancy, I've been taking these vitamins, and they've proven to be of excellent quality. My hair has stopped falling, my health feels robust, and I no longer suffer from relentless fatigue. There are no unpleasant aftertastes, and managing chronic fatigue syndrome has been much easier with these supplements. I'm grateful for their effectiveness.
Read More

Frequently Asked Questions

9
Improved energy levels
34 people found this helpful
The effect is clear. Since I began taking Omega and Vitamin D while breastfeeding my 2-month-old daughter, my fatigue and sleepiness have significantly lessened. I feel lively and no longer struggle to stay awake during the day. My hair remains healthy, and I’ve had no acne issues, which I was concerned about. I will continue taking these supplements as they truly boost my wellbeing.
7.5
Enhanced wellbeing
10 people found this helpful
This Omega product for mothers is excellent. The small, easy-to-swallow tablets have no unpleasant flavours. I can feel the advantages of Omega-3, which supports vital bodily functions and combats chronic fatigue syndrome. It has helped improve my energy levels and overall health, so I highly recommend it.
7.5
Healthy hair growth
During my third pregnancy, I've been taking these vitamins, and they've proven to be of excellent quality. My hair has stopped falling, my health feels robust, and I no longer suffer from relentless fatigue. There are no unpleasant aftertastes, and managing chronic fatigue syndrome has been much easier with these supplements. I'm grateful for their effectiveness.
7.5
Boosted cheerfulness
4 people found this helpful
This prenatal Omega with Vitamin D3 is great for pregnant and lactating women, ensuring proper brain development for the baby. The small capsules are easy to swallow with no fishy taste, and I’ve experienced no side effects. After taking them, I feel cheerful, which helps counteract chronic fatigue syndrome during this vital time.
9
Healthy baby outcome
I was diagnosed with Down syndrome and experienced complications during my pregnancy. Despite a difficult time, I regularly took this Omega 3 without any unpleasant side effects. It contributed significantly to my health, helping to protect against chronic fatigue syndrome, and I’m thrilled to have delivered a healthy baby. It's undoubtedly worth investing in these vital vitamins during pregnancy.
8
Beta-glucan shows cognitive improvements
We conducted a randomized, double-blind, placebo-controlled trial to explore how yeast beta-glucan, along with multivitamins, affects individuals suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In our study, 65 participants received either beta-glucan combined with vitamins and zinc or a placebo for 36 weeks.

Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.

Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.
We conducted a thorough investigation into whether high-dose intermittent vitamin D3 could alleviate symptoms of chronic fatigue syndrome (CFS) and improve vascular health. This double-blind, randomized placebo-controlled trial involved patients meeting established criteria for CFS. Participants received either 100,000 units of vitamin D3 or a placebo every two months for six months.

Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.

In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.
9.5
Eicosapentaenoic acid benefits CFS
We explored the potential benefits of eicosapentaenoic acid (EPA), an essential fatty acid, in treating chronic fatigue syndrome (CFS). A female patient with a six-year history of persistent CFS symptoms participated in the study, receiving a daily supplement rich in EPA.

After measuring her brain structure through high-resolution magnetic resonance imaging both at the beginning and 16 weeks later, we observed significant improvements in her symptoms starting just six to eight weeks into the treatment. Most notably, the patient's lateral ventricular volume—a key indicator of brain health—decreased from 28,940 mm³ to 23,660 mm³, indicating structural changes in her brain.

This research hints at the promising role of EPA in alleviating symptoms of chronic fatigue syndrome while also suggesting positive brain changes associated with treatment. The findings encourage further investigation into fatty acid supplementation's potential as an effective therapeutic strategy for CFS.
9
Eicosapentaenoic acid shows promise
We examined the link between chronic fatigue syndrome (CFS) and essential fatty acids, focusing specifically on eicosapentaenoic acid (EPA). This investigation arose from various studies highlighting the potential role essential fatty acids play in alleviating symptoms associated with CFS.

Our approach involved administering a high-EPA supplementation to a group of individuals diagnosed with chronic fatigue syndrome. After following these patients for eight to twelve weeks, we observed that all participants experienced notable improvements in their symptoms.

These positive changes align with recent findings that discuss both cerebral and clinical benefits tied to increased EPA intake. Given these encouraging results, eicosapentaenoic acid may ultimately provide hope for many suffering from chronic fatigue syndrome.
9
Effective treatment for fatigue syndrome
We conducted a thorough investigation into the effects of essential fatty acids, including eicosapentaenoic acid (EPA), on individuals suffering from postviral fatigue syndrome. In a well-structured trial, 63 adults with this condition participated in a double-blind, placebo-controlled study. They had been living with severe fatigue and other troubling symptoms for one to three years following a viral infection.

Patients received either an active treatment containing EPA and other essential fatty acids or a placebo for three months. Their overall health, fatigue levels, and other symptoms were assessed at the beginning, after one month, and at the end of the study. Strikingly, we observed that 74% of those taking the essential fatty acids reported improvements after one month, rising to 85% after three months. In contrast, only 23% and 17% of the placebo group noted any benefit at those respective time points.

Notably, the fatty acid levels in the participants' red blood cells, which were abnormal at the beginning of the trial, showed significant improvement with the active treatment. Importantly, we found no adverse side effects from the treatment, leading us to conclude that essential fatty acids can be a safe and effective option for people dealing with postviral fatigue syndrome.

References

  1. Lacasa M, Alegre-Martin J, Sentañes RS, Varela-Sende L, Jurek J, et al. Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2023;15. doi:10.3390/nu15214504
  2. Witham MD, Adams F, McSwiggan S, Kennedy G, Kabir G, et al. Effect of intermittent vitamin D3 on vascular function and symptoms in chronic fatigue syndrome--a randomised controlled trial. Nutr Metab Cardiovasc Dis. 2015;25:287. doi:10.1016/j.numecd.2014.10.007
  3. Puri BK. Long-chain polyunsaturated fatty acids and the pathophysiology of myalgic encephalomyelitis (chronic fatigue syndrome). J Clin Pathol. 2007;60:122.
  4. Maes M, Mihaylova I, Leunis JC. In chronic fatigue syndrome, the decreased levels of omega-3 poly-unsaturated fatty acids are related to lowered serum zinc and defects in T cell activation. Neuro Endocrinol Lett. 2005;26:745.
  5. Puri BK, Holmes J, Hamilton G. Eicosapentaenoic acid-rich essential fatty acid supplementation in chronic fatigue syndrome associated with symptom remission and structural brain changes. Int J Clin Pract. 2004;58:297.
  6. Puri BK. The use of eicosapentaenoic acid in the treatment of chronic fatigue syndrome. Prostaglandins Leukot Essent Fatty Acids. 2004;70:399.
  7. Behan PO, Behan WM, Horrobin D. Effect of high doses of essential fatty acids on the postviral fatigue syndrome. Acta Neurol Scand. 1990;82:209.
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