Medical Researches
Possibly Effective
Based on 9 Researches
Eicosapentaenoic acid benefits CFSEicosapentaenoic acid-rich essential fatty acid supplementation in chronic fatigue syndrome associated with symptom remission and structural brain changes.
High relevance to CFS treatment
We explored the potential benefits of eicosapentaenoic acid (EPA), an essential fatty acid, in treating chronic fatigue syndrome (CFS). A female patient with a six-year history of persistent CFS symptoms participated in the study, receiving a daily supplement rich in EPA.
After measuring her brain structure through high-resolution magnetic resonance imaging both at the beginning and 16 weeks later, we observed significant improvements in her symptoms starting just six to eight weeks into the treatment. Most notably, the patient's lateral ventricular volume—a key indicator of brain health—decreased from 28,940 mm³ to 23,660 mm³, indicating structural changes in her brain.
This research hints at the promising role of EPA in alleviating symptoms of chronic fatigue syndrome while also suggesting positive brain changes associated with treatment. The findings encourage further investigation into fatty acid supplementation's potential as an effective therapeutic strategy for CFS.
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We examined the link between chronic fatigue syndrome (CFS) and essential fatty acids, focusing specifically on eicosapentaenoic acid (EPA). This investigation arose from various studies highlighting the potential role essential fatty acids play in alleviating symptoms associated with CFS.
Our approach involved administering a high-EPA supplementation to a group of individuals diagnosed with chronic fatigue syndrome. After following these patients for eight to twelve weeks, we observed that all participants experienced notable improvements in their symptoms.
These positive changes align with recent findings that discuss both cerebral and clinical benefits tied to increased EPA intake. Given these encouraging results, eicosapentaenoic acid may ultimately provide hope for many suffering from chronic fatigue syndrome.
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We conducted a thorough investigation into the effects of essential fatty acids, including eicosapentaenoic acid (EPA), on individuals suffering from postviral fatigue syndrome. In a well-structured trial, 63 adults with this condition participated in a double-blind, placebo-controlled study. They had been living with severe fatigue and other troubling symptoms for one to three years following a viral infection.
Patients received either an active treatment containing EPA and other essential fatty acids or a placebo for three months. Their overall health, fatigue levels, and other symptoms were assessed at the beginning, after one month, and at the end of the study. Strikingly, we observed that 74% of those taking the essential fatty acids reported improvements after one month, rising to 85% after three months. In contrast, only 23% and 17% of the placebo group noted any benefit at those respective time points.
Notably, the fatty acid levels in the participants' red blood cells, which were abnormal at the beginning of the trial, showed significant improvement with the active treatment. Importantly, we found no adverse side effects from the treatment, leading us to conclude that essential fatty acids can be a safe and effective option for people dealing with postviral fatigue syndrome.
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We conducted a study to evaluate the effectiveness of essential fatty acids, particularly docosahexaenoic acid (DHA), in treating postviral fatigue syndrome, which affects many individuals after a viral infection.
In a double-blind, placebo-controlled setup involving 63 adults, we administered a mixture of essential fatty acids to half of the participants while the other half received a placebo. Each person received eight capsules daily for three months, and we checked their overall condition, fatigue, and other symptoms at various points throughout the study.
Excitingly, we observed significant improvements among those taking the active treatment. After just one month, 74% of participants in the DHA group felt better compared to only 23% in the placebo group. That number rose to 85% at the three-month mark, indicating that while the placebo group reverted to their initial state, those receiving essential fatty acids continued to improve.
Additionally, we saw that the fatty acid levels in patients’ blood cells normalized with treatment, and there were no adverse effects reported. Overall, our findings suggest that DHA, as part of a broader essential fatty acid approach, is a safe and beneficial option for those suffering from postviral fatigue syndrome.
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Beta-glucan shows cognitive improvementsYeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Vitamin D3 effects unclear
We conducted a randomized, double-blind, placebo-controlled trial to explore how yeast beta-glucan, along with multivitamins, affects individuals suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In our study, 65 participants received either beta-glucan combined with vitamins and zinc or a placebo for 36 weeks.
Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.
Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.
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